Science of the orgasm

As they seek to document and demystify one of life's great thrills, scientists have run across some real head-scratchers.

How, for example, can they explain the fact that some men and women who are paralyzed and numb below the waist are able to have orgasms?

How to explain the "orgasmic auras" that can descend at the onset of epileptic seizures -- sensations so pleasurable they prompt some patients to refuse antiseizure medication?

And how on Earth to explain the case of the amputee who felt his orgasms centered in that missing foot?

No one -- no sexologist, no neuroscientist -- really knows. For a subject with so many armchair experts, the human orgasm is remarkably mysterious.

But today, a few scientists are making real progress -- in part because they're changing their focus. To uncover the orgasm's secrets, researchers are looking beyond the clitoris, vagina, penis and prostate, to the place behind the scenes where the true magic happens. They're examining the central nervous system: the network of electrical impulses that zip to and fro through the brain and spinal cord.

In an orgasm orchestra, the genitalia may be the instruments, but the central nervous system is the conductor...[via]